2021 Mercedes-Benz E 450 recalls and problems

14 recalls and 7 owner complaints on file with NHTSA for the 2021 Mercedes-Benz E 450.

14
recalls
7
owner complaints
0
complaints mentioning a crash
0
mentioning a fire

Recalls apply to specific production ranges. To see whether a particular car still has an open recall, enter its VIN at nhtsa.gov/recalls. Repairs for safety recalls are free at authorised dealers.

2021 Mercedes-Benz E 450 recalls

Electrical system: wiring

NHTSA campaign 24V100000 · reported February 9, 2024 · Mercedes-Benz USA, LLC · 12,191 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 CLS450, E450, E450 All-Terrain, AMG E53, AMG GT43, AMG GT53, and 2021 AMG CLS53 vehicles. The 48-volt ground cable connection located in the engine compartment may not be tightened properly and may result in the ground cable overheating.
The risk
An overheated ground cable increases the risk of a fire.
The fix
Dealers will inspect the 48-volt ground cable connection and repair it as necessary, free of charge. Owner notification letters were mailed March 22, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024MMNNNN.

Electrical system: 12v/24v/48v battery

NHTSA campaign 22V733000 · reported September 30, 2022 · Mercedes-Benz USA, LLC · 19,968 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2022 CLS450 Coupe and AMG E53, 2019-2021 AMG CLS53 Coupe, and 2021-2022 E450 vehicles. The 12-Volt battery in the trunk may not be properly secured, which, in the event of a crash, can cause electrical connection failure, disabling various safety features including, emergency call (eCall) system, electric seat adjustment, hazard warning lights, and automatic door locks.
The risk
The inability to operate safety features (eCall system, hazard lights, electric seats, or automatic door locks) can increase the risk of injury during a crash.
The fix
Dealers will secure the 12V battery, free of charge. Owner notification letters were mailed January 20, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022100009.

Electrical system: software · Communication: auto crash notification

NHTSA campaign 22V365000 · reported May 20, 2022 · Mercedes-Benz USA, LLC · 242,722 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. An error in the communication module's SIM card software can cause a mobile network connection failure, disabling the emergency call (eCall) system.
The risk
A disabled eCall system would prevent a vehicle occupant from contacting the emergency services call center in an emergency, potentially delaying emergency responders and increasing the risk of injury.
The fix
The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022. Owner notification letters will be mailed in phases, on July 8, 2022, May 17, 2024, July 29, 2024, and September 27, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's numbers are for this recall is 2022060005 and 2023110006.

Back over prevention: display function

NHTSA campaign 22V232000 · reported April 8, 2022 · Mercedes-Benz USA, LLC · 126,443 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2018-2021 CLA-Class, GLE/GLS-Class, A-Class, C-Class, E-Class, E-Class Coupe/Convertible, GLA/GLB-Class, GLC-Class, and CLS-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The rearview camera may not display the rearview image due to a software error. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 111, "Rear Visibility."
The risk
An inoperable rearview camera display reduces the driver's rear view, increasing the risk of a crash.
The fix
Dealers will update the rearview camera software, free of charge. Owner notification letters were mailed July 15, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022060007.

Steering: steering wheel/handle bar

NHTSA campaign 22V189000 · reported March 25, 2022 · Mercedes-Benz USA, LLC · 8,396 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.
The risk
Deactivated hands-off detection will prevent DISTRONIC system features from functioning, including warnings to grab the steering wheel and calling first responders as part of the Active Emergency Stop Assist, which can increase the risk of a crash or injury.
The fix
Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040010.

Air bags: sensor, side impact

NHTSA campaign 21V527000 · reported July 12, 2021 · Mercedes-Benz USA, LLC · 542 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 CLS450, AMG E53, AMG CLS53, E350, E450, AMG GT43, AMG GT53, 2020 S450, S560, G550, AMG GLC63, 2020-2021 GLC300, and AMG G63 vehicles. The side crash sensor connectors may come loose, which could delay the activation of air bags and seatbelts during a side impact crash.
The risk
Air bags and seatbelts that don't function as intended can increase the risk of injury during a crash.
The fix
Dealers will inspect and replace as necessary, the side impact crash sensors, free of charge. Owner notification letters were mailed on September 3, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021070032/33.

Seat belts: rear/other, retractor

NHTSA campaign 21V483000 · reported June 25, 2021 · Mercedes-Benz USA, LLC · 4,917 vehicles potentially affected

The problem
Mercedes-Benz, LLC (MBUSA) is recalling certain 2021 G550, AMG G63, E350, E450, AMG CLS53, AMG E53, AMG GT43, AMG GT53, AMG GT63, 2021-2022 CLS450, and AMG E63 vehicles. The rear seat belt automatic locking retractors may deactivate early, which can prevent the child restraint system from securing properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 208, "Occupant Crash Protection."
The risk
An unsecured child restraint system can increase the risk of injury during a crash.
The fix
Dealers will inspect, and replace as necessary, the rear seat belt assemblies, free of charge. Owners notified of the voluntary recall campaign by an interim letter on August 13, 2021. A final letter was mailed on September 24, 2021. Owners may contact MBUSA customer service at 1-800-367-6372.

Seats: mid/rear assembly, head restraint

NHTSA campaign 21V406000 · reported May 28, 2021 · Mercedes-Benz USA, LLC · 218 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 C300 Cabriolet, C43 AMG Cabriolet, C63 AMG Cabriolet, C63 AMG S Cabriolet, E450 Cabriolet, and E53 AMG Cabriolet vehicles. The rear headrests may be incorrectly mounted to the seatbacks.
The risk
Incorrectly mounted headrests could move or detach from the seat during a crash, increasing the risk of injury.
The fix
Dealers will inspect the rear seatback guide bushings and replace them if necessary, free of charge. Owner notification letters were mailed July 16, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021060010.

Back over prevention: sensing system, camera · Electrical system: software

NHTSA campaign 21V354000 · reported May 14, 2021 · Mercedes-Benz USA, LLC · 343,191 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2021 CLA-Class, GLE/GLS-Class, A-Class, E-Class, E-Class Coupe and Convertible, GLA/GLB-Class, GLC-Class, CLS-Class, and AMG GT-Class 4-door Coupe vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The MBUX multimedia system software may cause the display to remain black, or reboot after startup. This could result in the rearview camera image not displaying properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) number 111, "Rear Visibility."
The risk
A backup camera that displays a blank image reduces the driver's rear view, increasing the risk of a crash or injury.
The fix
The multimedia system software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed beginning June 28, 2021. Owners may contact MBUSA customer service at 1-800-367-6373. MBUSA's number for this recall is 2021050012.

Back over prevention: warnings, external/pedestrian alert · Back over prevention: sensing system, camera

NHTSA campaign 21V228000 · reported April 1, 2021 · Mercedes-Benz USA, LLC · 6 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 E350, E450, E450 Wagon, and AMG E63 vehicles. The parking control unit may fail to display the rearview camera image and cause the parking sensors to misidentify or fail to detect objects.
The risk
An inoperative rearview camera display and/or parking sensors can reduce the driver's view and awareness of what is behind the vehicle, increasing the risk of a crash.
The fix
All affected vehicles are still within MBUSA's control. MBUSA will replace the parking control unit, free of charge. The recall began April 8, 2021. Owner may contact MBUSA customer service at 1-800-367-6372.

Seats · Seat belts: pretensioner · Air bags: sensor, occupant classification

NHTSA campaign 21V230000 · reported April 1, 2021 · Mercedes-Benz USA, LLC · 8,634 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 C-Class, E-Class, E-Class Coupe and Convertible, GLC, CLS, AMG GT 4-door Coupe and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. A faulty electrical contact within the seat position switch may prevent the driver and passenger air bags and seat belt force limiters from properly activating during a crash.
The risk
Air bags and seat belts that do not perform properly in a crash can increase the risk of injury.
The fix
MBUSA will notify owners, and dealers will replace the seat position switches, free of charge. Owner letters were mailed May 21, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021040016.

Seats: front assembly, power adjust · Seats

NHTSA campaign 21V216000 · reported March 26, 2021 · Mercedes-Benz USA, LLC · 109 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 E350, E450, E450 Wagon, E63S AMG, 2020 E63S AMG Wagon, and 2020-2021 E53 AMG vehicles. The passenger seat limiter may allow the seat to be positioned too close to the air bag.
The risk
A seat too close to the air bag increases the risk of injury in the event of a crash necessitating the deployment of the frontal passenger air bag.
The fix
MBUSA will notify owners, and dealers will recalibrate the passenger seat limiter, free of charge. The recall began April 29, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021040002.

Electrical system: software · Communication: auto crash notification

NHTSA campaign 21V058000 · reported February 5, 2021 · Mercedes-Benz USA, LLC · 1,292,258 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 - 2021 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, GT-Class, C-Class, E-Class, S-Class, CLS-Class, SL-Class, B-Class, GLB-Class, GLC-Class, and G-Class vehicles. Please refer to the Part 573 report for specific vehicle model details. The software design of the communication module may fail to communicate the correct vehicle location for the emergency call system (eCall) in the event of a crash.
The risk
Failure of the eCall system may result in emergency responders being dispatched to the wrong location, increasing the risk of injury following a crash.
The fix
MBUSA will notify owners, and the communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. The recall began March 12, 2021. Owners may contact MBUSA customer service at 1-877-762-8267. MBUSA's number for this recall is 2021020025.

Seats

NHTSA campaign 20V673000 · reported October 30, 2020 · Mercedes-Benz USA, LLC. · 1,337 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2021 E350 and E450, 2019-2021 AMG E53 and 2020-2021 AMG E63 vehicles. The front passenger seat may be missing the mechanical seat adjustment range limit stop, allowing the seat to move outside of the acceptable range in relation to the air bag.
The risk
If the front passenger seat is adjusted beyond the acceptable range in relation to the air bag, there could be an increased risk of injury in the event of a crash with air bag deployment.
The fix
MBUSA will notify owners, and dealers will inspect for the mechanical seat adjustment range limitation for the front passenger seat and install it if necessary, free of charge. The recall began December 18, 2020. Owners may contact MBUSA customer service at 1-800-368-6372. MBUSA's number for this recall is 2020110013.

Most reported problems

Areas named in owner complaints to NHTSA. One complaint can name several areas.

What owners report

Recent complaints filed with NHTSA, shortened. These are unverified accounts from owners, not findings.

Jun 23, 2022 · Wheels

After the car sits for three or more days, brakes locks up. It takes lots of power to get the brakes to release. It’s a safety concern as the car is parked in the garage with not enough room to maneuver. We never had any car which locks the brakes in this manner. Took it to MB dealer and they say it’s the way brakes…

Mar 23, 2022 · Unknown or other

Mercedes Benz issued a recall (Manufacturer Recall Number [phone removed]; NHTSA Recall Number 21V354) in May 2021. The recall affects my vehicle's MBUX multimedia system, most importantly, the backup camera, which may fail while in use if this issue is not remedied. I was advised of the recall by them in July 2021…

Dec 29, 2021 · Unknown or other · 1,000 miles

The contact owns a 2021 Mercedes-Benz E450. The contact stated that the vehicle speed control was always inadvertently activated, which caused the vehicle to decelerate automatically. The failure nearly caused a collision. The dealer was made aware of the failure and referred the contact to the manufacturer. The…

Nov 26, 2021 · Engine

The 48 volt battery on this mild hybrid vehicle failed and the car was unable to be started on May 3, 2021, with 196 miles on the odometer, a mere 15 days after delivery. It had to be taken by flatbed to the dealer where ultimately the 48 volt battery was replaced. Then again on June 5, 2021, the car was again unable…

Aug 3, 2021 · Electrical system

48Volt battery failed after three months and just 3,400 miles. I understand this is a recurring problem with Mercedes. Car had to be towed as the vehicle was totally inoperable due to battery malfunction. It took more than three weeks for Mercedes to provide a replacement battery. From what I have read, there is a…

E 450 model years compared

YearRecallsComplaintsCrashesFires
2019 121711
2020 7901
2021 14700
2022 51100
2023 41700
2024 4200

All Mercedes-Benz E 450 years →

Questions

Does the 2021 Mercedes-Benz E 450 have any recalls?
Yes. NHTSA lists 14 recalls for the 2021 Mercedes-Benz E 450, the most recent reported on February 9, 2024 (Electrical system: wiring). Check a specific car by its VIN at nhtsa.gov/recalls.
What are the most common problems with the 2021 Mercedes-Benz E 450?
Owners have filed 7 complaints with NHTSA. The most frequently reported area is electrical system (3 complaints), followed by engine (2).
How many 2021 Mercedes-Benz E 450 complaints mention a crash or fire?
0 of 7 complaints report a crash and 0 a fire; 0 injuries were reported in total. Complaints are unverified reports from owners.

Source: NHTSA recall and complaint data, updated October 27, 2026. Latest complaint received June 23, 2022.