2010 Mercedes-Benz E350 recalls and problems

4 recalls and 184 owner complaints on file with NHTSA for the 2010 Mercedes-Benz E350.

4
recalls
184
owner complaints
9
complaints mentioning a crash
0
mentioning a fire

Recalls apply to specific production ranges. To see whether a particular car still has an open recall, enter its VIN at nhtsa.gov/recalls. Repairs for safety recalls are free at authorised dealers.

2010 Mercedes-Benz E350 recalls

Engine and engine cooling: engine, engine control module (ECU/ECM), software · Electronic stability control (ESC): control module, software · Exterior lighting: lighting control module, software

NHTSA campaign 22V168000 · reported March 18, 2022 · Mercedes-Benz USA, LLC · 22 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2010 E350, 2014 G550, 2008-2009 C300, 2008 C350, 2009 CLK550, 2007 SL550, SLK280, and 2008 SLK350 vehicles. Various control units may have been updated with incorrect software configuration during a service repair. This can result in various system failures, such as loss of drive power, reduced exterior lighting, or loss of dynamic control functions, including stability and traction control.
The risk
Various system failures, such as loss of drive power, reduced exterior lighting, or loss of dynamic control functions including stability and traction control, can increase the risk of a crash.
The fix
Dealers will update the software configuration on the affected control units, free of charge. Owner notification letters were mailed May 3, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040003.

Air bags: frontal, passenger side, inflator module

NHTSA campaign 18V043000 · reported January 10, 2018 · Mercedes-Benz USA, LLC. · 132,167 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2013 C250, C250 Coupe, C350 Coupe 4Matic, C300 4Matic, C350, C350 Coupe, C63 AMG, C63 Coupe, E350 Cabrio, E350 Coupe, E550 Cabrio, E350 Coupe 4Matic, E550 Coupe, GLK350 4Matic, GLK250 Bluetec 4Matic, GLK350, SLS Coupe, SLS AMG GT Coupe, and SLS Roadster vehicles sold, or ever registered, in the states of Alabama, California, Florida, Georgia, Hawaii, Louisiana, Mississippi, South Carolina, Texas, Puerto Rico, American Samoa, Guam, the Northern Mariana Islands (Saipan), and the U.S. Virgin Islands or "Zone A." Additionally, MBUSA is recalling certain 2010 C300, C300 4Matic, C63 AMG, E350 Coupe, E550 Coupe, GLK350, and GLK350 4Matic vehicles ever registered in the states of Arizona, Arkansas, Delaware, District of Columbia, Illinois, Indiana, Kansas, Kentucky, Maryland, Missouri, Nebraska, Nevada, New Jersey, New Mexico, North Carolina, Ohio, Oklahoma, Pennsylvania, Tennessee, Virginia, and West Virginia or "Zone B." MBUSA is also recalling certain 2009 C300, C300 4Matic, C63 AMG, and C350 vehicles ever registered in the states of AK, CO, CT, ID, IA, ME, MA, MI, MN, MO, NH, NY, ND, OR, RI, SD, UT, VT, WA, WI and WY or "Zone C." In the event of a crash necessitating deployment of the passenger frontal air bag, these passenger air bag inflator may explode due to propellant degradation occurring after long-term exposure to absolute humidity and temperature cycling.
The risk
An inflator explosion may result in sharp metal fragments striking the driver or other occupants resulting in serious injury or death.
The fix
MBUSA will notify owners, and dealers will replace the passenger frontal air bag module, free of charge. Mercedes issued an interim notification to owners on February 23, 2018. A second notice will be mailed when remedy parts are available. Owners may contact MBUSA customer service at 1-877-496-3691.

Air bags: frontal, passenger side, inflator module

NHTSA campaign 16V363000 · reported May 26, 2016 · Mercedes-Benz USA, LLC. · 258,163 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC (MBUSA) is recalling certain model year 2008-2011 C300 Sedan, C300 4matic Sedan, C350 Sedan, C63 AMG Sedan vehicles, 2010-2011 GLK350, GLK350 4-Matic and E350 Coupe vehicles, 2011 SLS AMG, E350 Convertible, E550 Coupe and E550 Convertible vehicles originally sold, or ever registered, in Alabama, California, Florida, Georgia, Hawaii, Louisiana, Mississippi, South Carolina, Texas, Puerto Rico, American Samoa, Guam, the Northern Mariana Islands (Saipan), and the U.S. Virgin Islands, or "Zone A." Additionally, unless included in "Zone A" above, MBUSA is recalling certain model year 2008 C300 Sedan, C350 Sedan, C63 AMG Sedan and C300 4-Matic Sedan vehicles originally sold, or ever registered, in Arizona, Arkansas, Delaware, District of Columbia, Illinois, Indiana, Kansas, Kentucky, Maryland, Missouri, Nebraska, Nevada, New Jersey, New Mexico, North Carolina, Ohio, Oklahoma, Pennsylvania, Tennessee, Virginia, and West Virginia, or "Zone B." Vehicles not originally sold or ever registered in either Zones A or B are not subject to this safety recall. These vehicles are equipped with certain air bag inflators assembled as part of the passenger frontal air bag modules, and used as original equipment or replacement equipment. In the event of a crash necessitating deployment of the front air bags, these inflators may rupture due to propellant degradation occurring after long-term exposure to absolute humidity and temperature cycling.
The risk
An inflator rupture may result in metal fragments striking the vehicle occupants resulting in serious injury or death.
The fix
MBUSA will notify owners, and dealers will replace the passenger frontal air bag modules, free of charge. Owners were sent an interim notification October 2016. A second notice will be mailed when remedy parts are available. Owners may contact MBUSA customer service at 1-877-496-3691.

Air bags: frontal, driver side, inflator module

NHTSA campaign 16V081000 · reported February 11, 2016 · Mercedes-Benz USA, LLC. · 711,159 vehicles potentially affected

The problem
Mercedes-Benz USA, LLC. (MBUSA) is recalling certain model year 2009-2010 ML320 BlueTec 4Matic, GL320 BlueTec 4Matic and R320 CDI 4Matic, 2011 E350 Cabriolet and E550 Cabriolet, 2009-2011 ML350, ML350 4Matic, ML550 4Matic, ML63 AMG, and C63 AMG, 2010-2011 ML450 4Matic Hybrid, E350 Coupe, E350 4Matic, E550 Coupe, E550 4Matic, and E63 AMG, 2011-2012 GL350 BlueTec 4Matic and R350 BlueTec 4Matic, 2009-2012 GL450 4Matic, GL550 4Matic and R350 4Matic, 2007-2008 SLK280, SLK350, and SLK55 AMG, 2011-2014 SLS AMG Coupe, 2012 SLS AMG Cabriolet, 2013-2014 SLS AMG GT and SLS AMG GT Cabriolet, 2005 C230 Kompressor and C320, 2006-2007 C230, 2006-2011 C350, 2008-2011 C300 and C300 4Matic, 2010-2012 GLK350 and GLK350 4Matic and 2007-2008 Chrysler Crossfire vehicles. Upon deployment of the driver's frontal air bag, excessive internal pressure may cause the inflator to rupture.
The risk
In the event of a crash necessitating deployment of the driver's frontal air bag, the inflator could rupture with metal fragments striking the driver or other occupants resulting in serious injury or death.
The fix
MBUSA will their notify owners, and Fiat Chrysler will notify the affected Chrysler owners. Dealers for the respective brands will replace the driver's frontal air bag module, free of charge. This recall began November 2016. Mercedes-Benz owners may contact MBUSA customer service at 1-800-367-6372 and Chrysler owners may contact Fiat Chrysler customer service at 1-800-853-1403.

Most reported problems

Areas named in owner complaints to NHTSA. One complaint can name several areas.

What owners report

Recent complaints filed with NHTSA, shortened. These are unverified accounts from owners, not findings.

Sep 30, 2026 · Steering

While I was driving the Issues with the steering column module (SCM) sudden loss of critical driver controls, erratic electrical behavior. It failed to communicate properly with the power steering system, alongside dashboard warnings for the Electronic Stability Program (ESP) and Antilock Braking System (ABS) now my…

Apr 10, 2026 · Service brakes

I am writing to formally submit a complaint regarding my 2010 E350 (VIN # […] ). I have taken great pride in owning and maintaining this vehicle, and I want to share my concerns based on my recent experience. I have consistently kept this car well-maintained, following all recommended service schedules and ensuring…

Feb 17, 2026 · Exterior lighting

All of sudden blind spot inoperable , turning signal to Rt. , signal goes LT. OR TURNING SIGNAL TO LT. , SIGNAL GOES To RT.

Jan 19, 2026 · Service brakes

Car was found to have the rear subframe corrosion for issue. But also the brake lines were corroded very badly. They should be covered under the rear subframe extended warranty replacement. The rear brake lines are an frequent issue and almost always shows up when the subframe begins to rot. Also the pattern of the…

Nov 24, 2025 · Service brakes

It seems like brake lines corroded and need to be replaced. Same issue in this car with subframe and that was taken care of by the extended warranty but brake lines were not part of extended warranty? That should be investigated further. Rear subframe rust out and brake line corrosion are obviously related but…

E350 model years compared

YearRecallsComplaintsCrashesFires
2007 5350110
2008 417389
2009 46424
2010 418490
2011 522392
2012 721761
2013 6164154

Across all years, the 2006 E350 has the most complaints (400). All Mercedes-Benz E350 years →

Questions

Does the 2010 Mercedes-Benz E350 have any recalls?
Yes. NHTSA lists 4 recalls for the 2010 Mercedes-Benz E350, the most recent reported on March 18, 2022 (Engine and engine cooling: engine, engine control module (ECU/ECM), software, Electronic stability control (ESC): control module, software, Exterior lighting: lighting control module, software). Check a specific car by its VIN at nhtsa.gov/recalls.
What are the most common problems with the 2010 Mercedes-Benz E350?
Owners have filed 184 complaints with NHTSA. The most frequently reported area is air bags (68 complaints), followed by unknown or other (19).
How many 2010 Mercedes-Benz E350 complaints mention a crash or fire?
9 of 184 complaints report a crash and 0 a fire; 6 injuries were reported in total. Complaints are unverified reports from owners.

Source: NHTSA recall and complaint data, updated October 27, 2026. Latest complaint received September 30, 2026.